COMPARATIVE EVALUATION OF TOCOLYTIC THERAPY AND PERINATAL OUTCOMES IN PRETERM LABOR 

Abstract. This study presents a comparative assessment of the tocolytic effectiveness of oxytocin receptor blocker (atosiban), and selective beta-agonist (gexaprenalinum sulfatis) in patients with threatening preterm delivery and the impact of the therapy on perinatal outcomes in the studied groups. Studies have shown that the using of oxytocin receptor blocker (atosiban) has significant advantages in the management of preterm delivery compared with tocolytic therapy has been used earlier. Our method of premature labor prevention allows to prolong pregnancy for more than 7 days from the start of monotherapy (comprehensive endpoint of the study), to carry out the complete scheme of prevention of fetal RDS by the glucocorticoids and reduce its rate by 1.4 times.

Keywords: premature labor, tocolitic therapy, atosiban, perinatal outcomes 

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Authors
Ziyadinov Arsen A. Assistant of Professor ars-en@yandex.ua

Sulima Anna N.
Doctor of Medical Sciences, Associate Professor g_sulima@yandex.ua

The Department of Obstetrics, Gynecology and Perinatology, Medical Academy named after S.I. Georgievskiy “V.I. Vernadsky Crimean Federal University”
Russian Federation, 295006, the Republic of Crimea, Simferopol, Lenin avenue 5/7