Библиотека акушера

To gather and appraise the most recent evidence about the effectiveness of tocolysis to prevent bad perinatal outcomes in preterm births. A systematic literature review was carried out up to April 2016 along with the analysis of data presented during several international congresses.

Carbetocin, a long-acting oxytocin analogue, has been reported to elicit interesting and peculiar behavioural effects. The aim/purpose of this work was to investigate the molecular pharmacology of carbetocin in order to better understand the molecular basis of its action in the brain. Using Bioluminescence Resonance Energy Transfer (BRET) biosensors, we characterised the effects of carbetocin on the three human oxytocin/vasopressin receptors expressed in the nervous system: the oxytocin receptor (OXTR) and the vasopressin V1a (V1aR) and V1b (V1bR) receptors.

To compare the effectiveness of carbetocin and oxytocin when they are administered after caesarean section for prevention of postpartum haemorrhage (PPH).

To compare the e ectiveness of carbetocin with oxytocin with respect to maintain adequate uterine tone and to reduce the incidence and severity of postpartum haemorrhage. Moreover safety, adverse e ects and the need of additional medications were evaluated. Methods: Prospective controlled clinical trial.

A randomized study involving pregnant women was conducted to compare the eVectiveness of a single intravenous (IV) injection of carbetocin with that of a stan- dard 2-h oxytocin IV infusion with respect to intraoperative blood loss in the prevention of uterine atony after cesarean section (CS). The two treatments also were compared for safety and ability to maintain adequate uterine tone and to reduce the incidence and severity of postpartum hemor- rhage (PPH) in women at risk for this condition.

The main challenge in treating opioid addicts is to maintain abstinence due to the affective consequences associated with withdrawal which may trigger relapse. Emerging evidence suggests a role of the neurohypophysial peptide oxytocin in the modulation of mood disorders as well as drug addiction.